Antivirals — Flashcards

Flashcard 401: Highly active antiretroviral therapy (HAART) consists of a minimum of _____ drugs to prevent resistance

Answer: 3

Flashcard 402: Which class of HAART drugs inhibit HIV mRNA formation?_____

Answer: Integrase inhibitors

Flashcard 403: Which recombinant cytokine can be used to treat Kaposi sarcoma?

Answer: Interferon-α (IFN-α)

Extra: Interferon-α is a recombinant cytokine used in the treatment of Kaposi sarcoma (HHV-8), hairy cell leukemia, condyloma acuminatum (HPV), and chronic Hepatitis B and C.

Flashcard 404: Mycophenolate mofetil use can result in increased risk for _____ due to immunosuppression

Answer: invasive CMV infection

Flashcard 405: Which hepatitis drug has myelosuppression as a possible side effect?_____

Answer: Interferon alpha

Flashcard 406: Which antiviral can cause renal insufficiency and decreased serum Ca2+, Mg2+ and K+?_____

Answer: Foscarnet

Flashcard 407: Which HAART drugs can result in hyperlipidemia?_____

Answer: Protease inhibitors

Flashcard 408: IFN-α and IFN-β can cause a _____ that can be symptomatically managed with ibuprofen

Answer: flu-like syndrome

Flashcard 409: Do protease inhibitors require phosphorylation to be activated?_____

Answer: No

Flashcard 410: Which anti-influenza agent is useful in the management of Parkinson disease? _____

Answer: Amantadine