Antivirals US Medical PG Flashcards - Medical Study Cards
Master Antivirals with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Antivirals Flashcard Deck - 10 Cards
Flashcard 31: Protease inhibitors can result in hyperglycemia due to _____ resistance
Answer: insulin
Extra:
https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki
Flashcard 32: Valganciclovir, a prodrug of ganciclovir, has better oral _____
Answer: bioavailability
Extra:
https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki
Flashcard 33: Oseltamivir / zanamivir also prevent influenza by impairing viral penetration of _____ that overlie the respiratory epithelium
Answer: mucous secretions
Extra:
https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki
Flashcard 34: Which HAART drugs are associated with peripheral neuropathy?
_____
Answer: NRTIs; specifically stavudine and didanosine
Extra: NRTIs associated with peripheral neuropathy are primarily the 'd' drugs:
1. **Stavudine** (d4T)
2. **Didanosine** (ddI)
3. **Zalcitabine** (ddC) — rarely used now.
Lamivudine and Emtricitabine are generally considered to have the least mitochondrial toxicity and do NOT typically cause peripheral neuropathy.
Flashcard 35: What side effect presents with increased central adiposity with skinny legs?
_____
Answer: Lipodystrophy
Extra:
Watch Protease inhibitors [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antivirals-hiv-protease-inhibitors?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki
Flashcard 36: Ganciclovir and Valganciclovir are commonly used to treat _____
Answer: CMV
Extra:
Watch Ganciclovir, valganciclovir, foscarnet, cidofovir [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antivirals-other-ganciclovir-valganciclovir-foscarnet-cidofovir?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki
Flashcard 37: Which type of HAART drug is lamivudine (3TC)?
_____
Answer: NRTI
Extra:
Watch NRTIs [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antivirals-hiv-nrtis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki
Flashcard 38: Which anti-influenza drug increases dopamine synthesis/release and inhibits reuptake?
_____
Answer: Amantadine
Extra:
Watch Influenzavirus (Orthomyxoviridae) [https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-viruses/videos/medical-microbiology-viruses-rna-viruses-negative-sense-influenzavirus-orthomyxoviridae?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/neurology/videos/dementia?index=3]
https://onlinemeded.org/spa/infectious-disease?ref=anki
Flashcard 39: NRTIs are _____ inhibitors of the HIV Reverse Transcriptase
Answer: competitive
Extra:
https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki
Flashcard 40: Which step of the HIV life cycle do **NRTIs** target?
_____
Answer: Reverse transcription
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