Antivirals — Flashcards

Protease inhibitors can cause hyperlipidemia with _____ (increased central adiposity)

Foscarnet may induce _____ insufficiency (organ)

NS3/NS4A protease inhibitors and NS5A inhibitors are under clinical investigation to develop HCV treatment regimens that do not require _____ administration

NNRTIs have varying effects on _____ and thus may have many drug interactions

PEGylation of interferons allows what pharmacological property to be extended?_____

Resistance in CMV to ganciclovir occurs with mutations in the _____ gene

Lamivudine, tenofovir, and _____ can be used to treat HBV

Which strain(s) of influenza are treated with neuraminidase inhibitors (zanamivir, oseltamivir)?_____

Which DNA polymerase-inhibiting pyrimidine analog is used to treat hematologic malignancies only?

Which HAART drugs can result in hyperglycemia due to insulin resistance?_____