Antifungals US Medical PG Flashcards - Medical Study Cards
Master Antifungals with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Antifungals Flashcard Deck - 10 Cards
Flashcard 71: What class of antifungals prolong the QT interval?
_____
Answer: Azoles
Extra:
Watch Azoles [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antifungals-azoles?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/fungi/acquire?ref=anki
Flashcard 72: The antifungal class allylamines can be recognized via the suffix _____
Answer: -fine (e.g. terbinafine)
Extra:
Watch Griseofulvin, Terbinafine, Echinocandins [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antifungals-griseofulvin-terbinafine-echinocandins?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/fungi/acquire?ref=anki
Flashcard 73: Which antifungal works by disrupting mitotic spindles?
_____
Answer: Griseofulvin
Extra:
https://onlinemeded.org/spa/general-physiology/cytoskeleton/acquire?ref=anki
Flashcard 74: Griseofulvin inhibits the function of _____, resulting in metaphase arrest of cellular division
Answer: microtubules
Extra:
Watch Griseofulvin, Terbinafine, Echinocandins [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antifungals-griseofulvin-terbinafine-echinocandins?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/fungi/acquire?ref=anki
Flashcard 75: Oral candidiasis (thrush) can be treated with _____ ("swish and swallow")
Answer: Nystatin
Extra: Nystatin is a polyene antifungal.
Mechanism: Binds to ergosterol, forming pores in the fungal cell membrane that allow leakage of electrolytes.
Clinical use: Oral candidiasis (thrush), topical for diaper rash or vaginal candidiasis. Too toxic for systemic use.
Flashcard 76: Griseofulvin _____ cytochrome P-450
Answer: induces
Extra: Watch Griseofulvin, Terbinafine, Echinocandins: https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antifungals-griseofulvin-terbinafine-echinocandins
Flashcard 77: Systemic (disseminated) infections of coccidioidomycosis are treated with _____
Answer: Amphotericin B
Extra:
Watch Coccidioides immitis [https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-fungi/videos/medical-microbiology-fungi-systemic-mycoses-coccidioides-immitis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/fungi/acquire?ref=anki
Flashcard 78: What are the two topical azoles?
_____
Answer: Clotrimazole; Miconazole
Extra:
Watch Azoles [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antifungals-azoles?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/fungi/acquire?ref=anki
Flashcard 79: Which oral azole is used in the treatment of mucocutaneous candidiasis?
_____
Answer: Fluconazole
Extra:
Watch Azoles [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antifungals-azoles?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/fungi/acquire?ref=anki
Flashcard 80: Ketoconazole has anti-androgenic effects and thus can cause _____ in males
Answer: gynecomastia
Extra:
Watch Azoles [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antifungals-azoles?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/endocrinology/adrenals/acquire?ref=anki
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