Inflammation — Flashcards

Flashcard 41: Inflammatory vasculitides affecting the aorta (e.g. temporal arteritis, Takayasu arteritis) can lead to _____ formation

Answer: aortic aneurysm

Flashcard 42: Granulomatous diseases are associated with _____, due to increased 1α-hydroxylase in epithelioid histiocytes

Answer: hypercalcemia

Extra: * 1-alpha-hydroxylase is produced in the granulomas

Flashcard 43: Early involvement of cutaneous small-vessel vasculitis may present with _____

Answer: palpable purpura

Flashcard 44: In the setting of chronic inflammation, macrophages can be activated to M2 macrophages by stimulation from Th2 cells, resulting in a(n) _____ phenotype

Answer: antiinflammatory

Flashcard 45: Inflammation (e.g. meningitis/encephalitis), tumors, or late-stage stroke may cause cerebral edema resulting in _____ intracranial hypertension

Answer: vasogenic

Flashcard 46: Lymphocytosis often occurs in response to _____ infections

Answer: viral

Flashcard 47: Which peripheral nerve layer contains inflammatory infiltrate in Guillain-Barré syndrome? _____

Answer: Endoneurium

Flashcard 48: What microscopic changes occur from 1 - 3 days post-MI? _____

Answer: Neutrophils (acute inflammation)

Extra: * may also see punctate hemorrhages on histology

Flashcard 49: What histological findings are associated with Subacute thyroiditis (de Quervain)? _____

Answer: Granulomatous inflammation

Extra: Atlas:

Flashcard 50: The key mediators of redness and warmth in inflammation are _____, prostaglandins, bradykinin and NO

Answer: histamine