General Pathology — Flashcards

Flashcard 41: When HLA typing, the purpose of the Microcytotoxicity test is to test for MHC class _____

Answer: I (ex HLA-A, HLA-B)

Flashcard 42: What cell type never enters G0 and divides rapidly with a short G1? _____

Answer: Labile

Flashcard 43: Myotonic Dystrophy involves an abnormal expression of _____

Answer: myotonin protein kinase

Extra: * due to mutation in the DMPK gene

Flashcard 44: The _____ Coombs test adds donor blood and anti-Ig antibody (Coombs reagent) to the patient's serum

Answer: indirect

Extra: Other:

Flashcard 45: What laboratory technique is used to diagnose chromosomal imbalances? _____

Answer: Karyotyping

Flashcard 46: Cutaneous healing by _____ intention results in scar formation

Answer: secondary

Flashcard 47: The constant cycles of demyelination and remyelination seen in Charcot-Marie-Tooth disease result in unique histologic findings, including a(n) "_____" appearance around nerves that innervate muscles

Answer: onion bulb

Flashcard 48: Autoimmunity can be triggered by release of normally sequestered _____

Answer: antigens

Extra: * e.g. intracellular antigens exposed as a result of cell damage

Flashcard 49: Amyloidosis is characterized by _____ under polarized light after staining with Congo red

Answer: apple-green birefringence

Flashcard 50: Which type of calcification occurs in normal, non-necrotic tissues? _____

Answer: Metastatic