Edema mechanisms — Flashcards

Flashcard 1: Chediak-Higashi syndrome is characterized by _____ circulating neutrophils

Answer: decreased

Flashcard 2: Infarction and/or neoplasm of the blood-brain-barrier destroys endothelial cell tight junctions, causing _____

Answer: vasogenic edema

Flashcard 3: _____ is defined as separation of epidermal cells (e.g. Pemphigus vulgaris)

Answer: Acantholysis

Flashcard 4: Proliferation of the T cell compartment of lymph nodes causes _____ hyperplasia (e.g. viral infections)

Answer: paracortex

Flashcard 5: Ehlers-Danlos syndrome is characterized by faulty collagen synthesis causing _____ skin

Answer: hyperextensible

Flashcard 6: fat necrosis (breast)

Answer: fat necrosis and saponification following trauma (often mild or unremarkable trauma)

Extra: Presents as a painless breast lump; may mimic breast cancer on physical exam and mammography (calcifications from saponification).

Flashcard 7: The subtypes of fibrocystic disease of the breast are _____, _____, _____, and _____.

Answer: fibrosis

Flashcard 8: aplasia (organogenesis)

Answer: absent organ despite present primordial tissue

Flashcard 9: What is the ultimate consequence of prolonged nutrient depletion and waste build-up in a cell?

Answer: Death (Irreversible cell injury)

Extra: Prolonged nutrient depletion and waste build-up in a cell eventually leads to irreversible injury and cell death.

Flashcard 10: How do Duchenne's and Becker's muscular dystrophies differ genetically?

Answer: DMD: Frameshift mutation (complete loss of dystrophin). BMD: Non-frameshift mutation (partially functional dystrophin).