General Pathology — Flashcards

Flashcard 251: Beta-thalassemia major may be associated with _____ RBCs on blood smear.

Answer: Nucleated RBCs

Flashcard 252: In flow cytometry, antibodies are tagged with a unique _____, which is detected and counted during analysis

Answer: fluorescent dye

Flashcard 253: Patients with infective endocarditis can develop a nephritic syndrome due to deposition of _____

Answer: circulating immune complexes

Flashcard 254: G6PD deficiency is characterized primarily by _____ hemolysis

Answer: intravascular

Flashcard 255: What is typically the mode of inheritance of Charcot-Marie-Tooth disease? _____

Answer: Autosomal dominant

Flashcard 256: Direct Coombs Positive Hemolytic Anemia that develops as a result of Penicillin administration is a type _____ hypersensitivity rxn

Answer: II

Flashcard 257: Patients with Chediak-Higashi syndrome have increased risk for _____ infections (e.g. staphylococci and streptococci)

Answer: pyogenic

Flashcard 258: _____ is defined as hyperkeratosis with retention of nuclei in the stratum corneum (e.g. psoriasis)

Answer: Parakeratosis

Flashcard 259: Proliferation of the T cell compartment of lymph nodes causes _____ hyperplasia (e.g. viral infections)

Answer: paracortex

Flashcard 260: Which error in morphogenesis is characterized by extrinsic disturbance due to mechanical forces (usually occurring after the embryonic period)?

Answer: Deformation

Extra: Errors in Morphogenesis: • Malformation: Intrinsic disruption; occurs during the embryonic period (weeks 3–8). • Disruption: Secondary breakdown of previously normal tissue or structure (e.g., amniotic band syndrome). • Deformation: Extrinsic disturbance; caused by abnormal mechanical forces (e.g., uterine crowding) after the embryonic period. • Sequence: A cascade of anomalies starting from a single primary developmental error (e.g., Potter sequence).