Mutant 1-antitrypsin polymerizes and accumulates in the _____ of hepatocytes, resulting in liver damage (e.g. cirrhosis)
What pathology is associated with decreased telomerase activity?_____
The nucleus of apoptotic cells stains deeply _____-philic
Which type of necrosis resembles mummified tissue?_____
Niemann Pick disease may present with progressive _____
What type necrosis is seen with brain infarcts and abscess? _____
After 30 minutes of total myocardial ischemia, is ischemic injury reversible?_____
Which type of necrosis is characterized by necrotic damage to blood vessel walls? _____
Which type of necrosis is characterized by a chalky-white appearance due to deposition of Ca2+? _____
Chromatolysis is characterized by dispersion of _____ throughout the cytoplasm
Reversible cell injury mechanisms
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Irreversible cell injury (necrosis)
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Types of necrosis (coagulative, liquefactive, etc.)
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Apoptosis pathways
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Autophagy mechanisms
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Cellular adaptations (atrophy, hypertrophy)
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Hyperplasia and metaplasia
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Dysplasia
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Intracellular accumulations
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Pathologic calcification
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Cellular aging mechanisms
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Ischemia-reperfusion injury
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Free radical injury
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