Cell injury — Flashcards

Flashcard 191: What is the end result of irreversible cell injury?_____

Answer: Cell death

Flashcard 192: One theory behind the etiology of endometriosis is _____ transformation of multipotent cells

Answer: metaplastic

Flashcard 193: Which cellular change is characterized by disordered, non-neoplastic cellular growth? _____

Answer: Dysplasia

Flashcard 194: Which type of necrosis is associated with tuberculosis and fungal infections? _____

Answer: Caseous necrosis

Extra: Caseous necrosis is a hallmark of granulomatous inflammation (e.g., TB, Histoplasma). It is described as a combination of coagulative and liquefactive necrosis. Contrast this with **liquefactive necrosis**, which is seen in pyogenic abscesses (e.g., *Nocardia*, *S. aureus*), brain infarcts, and acute pancreatitis.

Flashcard 195: Which type of necrosis is characterized by preserved cell shape and organ structure? _____

Answer: Coagulative necrosis

Flashcard 196: Chromatolysis is characterized by displacement of the _____ to the periphery

Answer: nucleus

Flashcard 197: Is damage in the zone of stasis / edema reversible (and if yes, does it need treatment)?_____

Answer: Yes, with treatment

Flashcard 198: Mitochondrial _____ signifies irreversible cellular injury

Answer: vacuolization

Flashcard 199: Mutant \u03b11-antitrypsin polymerizes and accumulates in the _____ of hepatocytes, resulting in liver damage (e.g. cirrhosis)

Answer: endoplasmic reticulum

Flashcard 200: Apoptosis is characterized morphologically by cell _____ (size), chromatin condensation, and membrane blebbing

Answer: shrinkage