Cell injury — Flashcards

Flashcard 131: Crystals and _____ cells on urine microscopy are findings consistent with crystal-induced acute kidney injury

Answer: white blood

Extra:  https://onlinemeded.org?ref=anki 

Flashcard 132: What pathologic RBC is seen with end-stage renal disease and liver disease? _____

Answer: Echinocyte ("burr cell")

Extra:  https://onlinemeded.org?ref=anki 

Flashcard 133: Ischemic necrosis of the extremities (e.g., toes) is referred to as _____.

Answer: gangrene

Extra: Gangrenous necrosis is a clinical term applied to a limb (usually the lower leg) that has lost its blood supply and has undergone necrosis (typically coagulative necrosis). If bacterial infection is superimposed, it is called wet gangrene due to the liquefactive action of the bacteria and leukocytes.

Flashcard 134: _____ edema is caused by the failure of ATP-dependent transport of sodium and calcium ions across the cell membrane, causing accumulation of water and swelling _____ edema is caused by breakdown of the blood-brain barrier

Answer: Cytotoxic

Extra:  https://onlinemeded.org?ref=anki 

Flashcard 135: Painless breast lump 2° to trauma is caused by _____

Answer: fat necrosis

Extra:  https://onlinemeded.org/spa/surgery?ref=anki 

Flashcard 136: Protein aggregates in neurons from hyperphosphorylation of tau protein: _____

Answer: Pick bodies (Pick's Disease) and Neurofibrillary tangles (Alzheimer disease)

Extra:  https://onlinemeded.org/spa/neurology/dementia/acquire?ref=anki 

Flashcard 137: _____ presents with a triad of peripheral neuropathy, angiokeratomas, and hypohidrosis (lack of sweat)

Answer: Fabry disease

Extra:  https://onlinemeded.org?ref=anki 

Flashcard 138: What lysosomal storage disease presents with globoid cells?_____

Answer: Krabbe disease

Flashcard 139: Which type of calcification (dystrophic or metastatic) occurs secondary to injury or necrosis? _____

Answer: Dystrophic

Flashcard 140: Loss of dystrophin (e.g. X-linked muscular dystrophy) results in myo-_____

Answer: necrosis