Cardiovascular — Flashcards

Flashcard 21: What RBC morphology is present in hemolytic uremic syndrome (HUS)? _____

Answer: Schistocytes (helmet cells)

Flashcard 22: Normocytic anemia with intra-vascular hemolysis may cause leakage of hemoglobin into the _____ and _____

Answer: blood

Extra: *intravascular hemolysis releases free Hb (half the size (32 kDa) vs. intracellular Hb (64 kDa)-> can pass through the GBM -> Red Urine Other:

Flashcard 23: _____ ischemic strokes are due to hypoperfusion or hypoxemia; common during cardiovascular surgeries

Answer: Hypoxic

Extra: Atlas:

Flashcard 24: _____ dementia is a result of multiple arterial infarcts and/or chronic ischemia (e.g. hypertension, atherosclerosis, vasculitis)

Answer: Vascular

Extra: Atlas:

Flashcard 25: _____ anemia occurs due to damage of RBCs as they pass through obstructed or narrowed vessels (e.g. due to microthrombi)

Answer: Microangiopathic hemolytic

Extra: Other:

Flashcard 26: Ischemia can occur due to decreased _____ perfusion

Answer: arterial

Flashcard 27: Ristocetin induces platelet aggregation by causing _____ to bind platelet GPIb

Answer: vWF

Flashcard 28: Thoracic aortic aneurysm is classically seen in patients with _____ due to endarteritis of the vasa vasorum

Answer: tertiary syphilis

Extra: Atlas:

Flashcard 29: In TTP, large, uncleaved vWF multimers lead to increased platelet _____ with consequent microthrombi formation

Answer: adhesion

Flashcard 30: Senile cardiac amyloidosis is characterized by deposition of non-mutated _____ protein

Answer: transthyretin (TTR)