Gastroenterology — Flashcards

Flashcard 1031: Does eosinophilic esophagitis respond to GERD therapy (e.g. PPIs)?

Answer: Yes

Extra: Current guidelines (ACG/AGA) recognize PPIs as a **first-line treatment option** for eosinophilic esophagitis (EoE), alongside topical steroids (budesonide/fluticasone) and dietary elimination. Previously, a response to PPIs was used to distinguish "PPI-responsive esophageal eosinophilia" from "true" EoE, but these are now considered part of the same EoE disease spectrum.

Flashcard 1032: Which cause of genital ulceration presents with painless red genital ulcer that bleeds on contact?_____

Answer: Granuloma inguinale/donovanosis (Klebsiella granulomatis)

Flashcard 1033: _____ effects of blastomycosis typically occur when patients are in an immunocompromised state

Answer: Systemic

Flashcard 1034: Lichen planus often presents on the wrists, ankles, and _____ mucosa

Answer: oral

Flashcard 1035: _____ ulcers (gastric or duodenal) should be biopsied at the margins to rule out malignancy

Answer: Gastric

Flashcard 1036: Dermatomyositis can present as a paraneoplastic syndrome associated with _____

Answer: adenocarcinomas

Flashcard 1037: Prolonged vitamin B12 deficiency causes irreversible _____ damage

Answer: nerve

Flashcard 1038: Sjogren syndrome classically presents with _____, known as xerostomia

Answer: dry mouth

Flashcard 1039: Disorders of primary hemostasis present with symptoms of mucosal bleeding, such as _____ (most common overall symptom)

Answer: epistaxis

Flashcard 1040: Sjogren syndrome is associated with increased risk for _____, which presents as unilateral enlargement of the parotid gland late in the disease course

Answer: MALT lymphoma