Molecular Genetics — Flashcards

_____ describes the increased severity or earlier onset of a disease in succeeding generations

What is the mode of inheritance of type III familial dyslipidemia?_____

What enzyme is targeted by anti-Scl-70 antibodies? _____

In females, one of two X-chromosomes is condensed and its genes turned off by _____, forming heterochromatin (lyonization)

The most common type of Charcot-Marie-Tooth (CMT1A) is a duplication of large region of 17p which results in a mutation of _____

What chromosome is Ig heavy chain located on? _____

What type of oncogene is JAK2?_____

Is DNA synthesis high or low fidelity? _____

A _____ is type of DNA mutation in which a purine is mutated to another purine (or pyrimidine to pyrimidine)

What is the mode of inheritance of cystic fibrosis? _____