Molecular Genetics — Flashcards

Is adrenoleukodystrophy an X-linked or autosomal defect?_____

What enzyme is targeted by anti-Scl-70 antibodies? _____

What class of DNA mutations are characterized by a single nucleotide change? _____

What is the mode of inheritance of type III familial dyslipidemia?_____

The NF1 tumor suppressor gene normally codes for neurofibromin, a negative regulator of _____

What two types of variations in DNA are detected when using microarrays? (DNA markers)_____

What type of oncogene is JAK2?_____

_____ describes the increased severity or earlier onset of a disease in succeeding generations

What chromosome is Ig heavy chain located on? _____

_____thalasemmia is usually due to gene _____