Molecular Genetics — Flashcards

If mutations at different loci can produce a similar phenotype, a disease has _____

Factor V Leiden is due to a point mutation near the _____ site of factor V

Autosomal dominant diseases are often due to defects in _____ genes

The 5 to 3' exonuclease activity of prokaryotic DNA polymerase I is to remove the _____

Administration of hydroxyurea can lead to a build-up of _____ or CTP in the cell

How many primers are needed for polymerase chain reaction (PCR)? _____

Which type of antibody digestion results in 2 monovalent Fab regions and 1 Fc region? _____

Is mitochondrial DNA circular or linear?_____

What is the mode of inheritance of medium chain acyl-CoA dehydrogenase (MCAD) deficiency? _____

A mutation in Rb results in constitutively free _____, leading to uncontrolled cell cycle progression