Molecular Genetics — Flashcards

What is the penetrance of neurofibromatosis I? _____

What is the mode of inheritance of IL-12 deficiency? _____

What is the mode of inheritance of Hunter syndrome?_____

If a male has an X-linked dominant disease, all of his daughters will be _____

What is the mode of inheritance of sickle cell anemia? _____

25% of cases of Prader-Willi syndrome are due to _____ uniparental disomy

What form of hemoglobin protects against sickling in sickle cell anemia? _____

What cell type enters G1 from G0 when stimulated?_____

Which type of gene deletion (cis or trans) is associated with an increased risk of severe thalassemia in offspring? _____

What is the most common cause (95%) of Down syndrome? _____