Molecular Genetics — Flashcards

Flashcard 301: Why is the dystrophin (DMD) gene prone to spontaneous mutations? _____

Answer: Largest protein-coding human gene

Extra: Atlas:

Flashcard 302: What kind of inheritance do patients with androgenetic alopecia exhibit? _____

Answer: Polygenic

Flashcard 303: What type of oncogene is HER2/neu (c-erbB2)? _____

Answer: Epidermal growth factor receptor

Flashcard 304: Antidiuretic hormone (ADH) is packaged with neurophysin _____ and glycoprotein

Answer: II

Flashcard 305: The most common CFTR gene mutation (cystic fibrosis) results in a misfolded protein that is retained in the _____

Answer: RER

Flashcard 306: Sickle cell _____ is characterized by the presence of only one mutated β-chain

Answer: trait

Extra: Other:

Flashcard 307: The _____ chain contributes to the Fab and Fc region of an antibody

Answer: heavy

Flashcard 308: HDAC inhibitors prevent histones from being _____ resulting in genes such as tumor suppressors being transcribed

Answer: deacetylated

Extra: #REF!

Flashcard 309: Which gene of embryogenesis is involved in patterning along the anteroposterior axis and CNS development? _____

Answer: Sonic hedgehog gene

Flashcard 310: There are _____ total β-globin alleles present on chromosome 11

Answer: two

Extra: Atlas: Other: