Molecular Genetics — Flashcards

Flashcard 271: What type of oncogene is RAS? _____

Answer: GTP-binding protein (signal transducer)

Extra: RAS is a signal transducer that cycles between an active GTP-bound state and an inactive GDP-bound state.

Flashcard 272: Which enzyme is responsible for elongating the DNA strand? _____

Answer: DNA polymerase (specifically, DNA polymerase III in prokaryotes)

Flashcard 273: "Barr bodies" formed by lyonization may be visible where in the cell? _____

Answer: Periphery of the nucleus

Flashcard 274: What is another name for prokaryotic topoisomerase II? _____

Answer: DNA gyrase

Flashcard 275: Sickle cell trait results in _____ 50% HbS in RBCs

Answer: <

Extra: Other:

Flashcard 276: A(n) _____ mutation occurs when a nucleotide substitution codes for a different amino acid

Answer: missense

Flashcard 277: Once levels of Cyclins reach an appropriate level, these complex with _____ to hyperphosphorylate Rb

Answer: Cyclin-Dependent Kinases

Flashcard 278: A(n) _____ is a DNA sequence which reads the same backwards and forwards on opposite strands of DNA (usually 4 or 6 bp)

Answer: palindrome

Flashcard 279: What sequence of nucleotides is repeated in Fragile X syndrome? _____

Answer: CGG

Flashcard 280: Does a uniparental disomy result in euploidy or aneuploidy? _____

Answer: Euploidy