Molecular Genetics — Flashcards

_____ is the exchange of genetic material between homologous chromosomes

p53 induces apoptosis by activating _____ and _____, which dimerize and form a pore in the outer mitochondrial membrane

NF-kB activation pathway: the cascade of NF-kB activation is self limiting, as NF-kB stimulates transcription of more _____

What gene is defective in Menkes disease? _____

Lac Operon: Increased cAMP (low glucose) leads to activation of _____, which resides upstream from the promoter, causing increased transcription

Major histocompatibility complexes (MHCs) are encoded by _____ genes

Myotonic dystrophy is due to abnormal expression of the enzyme _____

Down syndrome presents with _____ free β-hCG

NF2 is a tumor suppressor gene that encodes for the protein _____

Hereditary pancreatitis may be caused by mutations in the cleavage site of trypsinogen or the _____ protein