Metabolism — Flashcards

A scientist is studying biochemical reaction that take place in the liver. -He cultures hepatocytes with glutamate labeled with nitrogen isotopes -After some times, he finds that the nitrogen isotopes are transferred to oxaloacetate forming aspartate. -Which vitamins is most likely involved in this reaction?

#790

What are the followings in relation to vitamin deficiency? -Abnormal oxidative decarboxylation of ketoacids. -Abnormal proline hydroxylation -Abnormal transamination -deficient methionine synthesis -Diminished synthesis of purines

Metabolism US Medical PG Flashcards - Medical Study Cards

Master Metabolism with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.

Metabolism Flashcard Deck - 10 Cards

Flashcard 781: What is the normal range of Amylase, serum?

Answer: From 25 to 125 U/L

Flashcard 782: What is the normal range of Urine: 17-Hydrocorticosteroids (Male)?

Answer: From 3.0 to 10.0 mg/24 hr

Flashcard 783: What is the normal range of Urine: Sodium?

Answer: From 0 to Varies with diet mEq/L

Flashcard 784: What is the normal range of CSF: Glucose?

Answer: From 40 to 70 mg/dL

Flashcard 785: What is the normal range of Urine: 17-Hydrocorticosteroids (Female)?

Answer: From 2.0 to 8.0 mg/24 hr

Flashcard 786: What is the normal range of Bicarbonate (HCO3-), serum?

Answer: From 22 to 28 mEq/L

Flashcard 787: What is the normal range of Creatinine kinase, serum (Male)?

Answer: From 25 to 90 U/L

Flashcard 788: What are the followings in relation to gluconeogenesis? -Acetoacetyl CoA ---> 3-hydroxy-3-methylglutaryl-CoA -Acetyl CoA ---> palmitic acid -Fructose 6-phosphate ---> fructose 1,6-bisphosphate -Glycogen ---> glucose-1-phosphate -Oxaloacetate ---> phosphoenolpyruvate

Answer: Acetoacetyl CoA --> HMG-CoA: to synthesize cholesterol and ketone bodies. Can't synthesize glucose. -Acetyl CoA --> Palmitic acid: 1st fatty acids synthesize from acetyl coa during prolong fasting. -Fructose 6 phosphate ---> Fructose 1,6-bisphosphate: Glycolysis, not gluconeogenesis. Gluconeogenesis: fructose 1,6-bisphosphate to fructose 6 phosphate by fructose 1,6 bisphosphatase. -Glycogen ---> glucose-1-phosphate: glycogenolysis, after 24 hours of fasting. There will not be any glycogen left in storage to lysis to glucose. Instead, the best reaction is gluconeogenesis, which means from oxaloacetate to phosphoenolpyruvate, going up and so on to make glucose. -Oxaloacetate ---> Phosphoenolpyruvate: best reaction after 24 hours to make glucose. (Gluconeogenesis)

Flashcard 789: A scientist is studying biochemical reaction that take place in the liver. -He cultures hepatocytes with glutamate labeled with nitrogen isotopes -After some times, he finds that the nitrogen isotopes are transferred to oxaloacetate forming aspartate. -Which vitamins is most likely involved in this reaction?

Answer: Pyridoxine (vit B6) because it's a common cofactor for conversion of amino acids (glutamate) into alpha keto acid (Oxaloacetate) and convert to Aspartate (AA). (Transaminase)

Flashcard 790: What are the followings in relation to vitamin deficiency? -Abnormal oxidative decarboxylation of ketoacids. -Abnormal proline hydroxylation -Abnormal transamination -deficient methionine synthesis -Diminished synthesis of purines

Answer: Abnormal oxidative decarboxylation: Thiamine (B1) deficiency -Abnormal proline hydroxylation: vit. C deficiency -Abnormal transamination: Vit. B6 (pyridoxine) deficiency -Deficient methionine synthesis: Vit. B12 (cobalamine) deficiency. -Diminished synthesis of purines: Vit B9 (folate) deficiency

Keywords: Metabolism flashcards, medical flashcards, NEET PG preparation, USMLE Step 1 flashcards, Anki alternative, spaced repetition medical, OnCourse flashcards

Study by Chapter

TCA cycle reactions and regulation

Flashcards

Electron transport chain and oxidative phosphorylation

Flashcards

Pentose phosphate pathway

Flashcards

Gluconeogenesis

Flashcards

Glycogen metabolism

Flashcards

Amino acid metabolism

Flashcards

Integration of metabolic pathways

Flashcards

Fed state vs. fasting state metabolism

Flashcards

Exercise metabolism

Flashcards

Alcohol metabolism

Flashcards

Metabolic adaptations in starvation

Flashcards

Metabolic disorders overview

Flashcards

Want unlimited flashcards?

Get full access to all flashcards, spaced repetition, and progress tracking.

Start For Free