DNA repair — Flashcards

Nonhomologous End Joining (NHEJ) occurs _____ S phase of the cell cycle

Which base excision repair enzyme is responsible for removing nucleotides at the 3' end?_____

What phase of the cell cycle do mismatch base repairs predominantly occur?_____

What form of DNA repair fixes mutations due to DNA replication errors?_____

Mechanisms to repair _____ breaks are defective in Ataxia telangiectasia, Fanconi anemia, and SCID

Is homologous recombination error prone?_____

Non-ionizing radiation causes carcinogenesis by generating _____

Chronic exposure to Arsenic may cause cancer by metabolites (ex. Dimethyl-Arsenic) inhibiting _____ motifs in Base-Excision Repair and Nucleotide-Excision Repair enzymes

Slippage in a template strand will cause a(n) _____

Polycyclic Aromatic Hydrocarbons (PAH) cause carcinogenesis through their metabolites forming DNA _____