DNA repair — Flashcards

MUTYH-associated polyposis is a(n) _____ syndrome with multiple colorectal adenomas and an increased risk of colorectal cancer

Hint: inheritance

Recognition and facilitation of excision of mismatched nucleotides occur via enzymes found on two genes: _____ or _____

The enzymes that repair pyrimidine dimer mutations are _____ and _____

In base excision repair, base-specific _____ remove the altered base and create a(n) AP (apurinic/apyrimidinic) site

What form of DNA repair fixes mutations induced by UV radiation? _____

The enzyme that recognizes and excises pyrimidine dimer mutations is _____

Homologous Recombination occurs _____ S phase of the cell cycle, using a(n) sister chromatid as a template

Hint: before/after?

What form of DNA repair fixes mutations due to DNA replication errors? _____

Nonhomologous End Joining is defective in _____ and Ataxia Telangiectasia

The _____ is involved in regulating Homologous Recombination, and when mutated causes Bloom syndrome