DNA repair — Flashcards

Flashcard 31: Xeroderma Pigmentosum is inherited in a(n) _____ fashion

Answer: autosomal recessive

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Flashcard 32: What phase of the cell cycle do base excision repairs occur?_____

Answer: Throughout the cell cycle

Flashcard 33: What form of DNA repair fixes mutations induced by UV radiation?_____

Answer: nucleotide excision repair

Flashcard 34: The _____ is involved in regulating Homologous Recombination, and when mutated causes Bloom syndrome

Answer: BLM helicase

Flashcard 35: What form of DNA repair fixes mutations due to spontaneous/toxic deamination?_____

Answer: Base excision repair

Flashcard 36: Which base excision repair enzyme is responsible for removing nucleotides at the 5' end?_____

Answer: AP-endonuclease

Flashcard 37: What phase of the cell cycle do nucleotide excision repairs occur?_____

Answer: G1

Flashcard 38: Is Nonhomologous End Joining error prone?_____

Answer: Yes

Flashcard 39: The enzyme that recognizes and excises pyrimidine dimer mutations is _____

Answer: excision endonuclease

Flashcard 40: When using CRISPR/Cas9 that introduce a double strand break to knock-out target DNA, _____ repair the gap introduced by this Cas9 variant

Answer: nonhomologous end joining enzymes