Safe Prescribing — Flashcards

Flashcard 61: _____ is a competitive μ-opioid receptor antagonist

Answer: Naloxone

Flashcard 62: What is the management of carbon monoxide poisoning? _____

Answer: 100% normobaric oxygen via non-rebreathe mask (minimum 6 hours)

Flashcard 63: What ABG result would you expect in a paracetamol overdose? _____

Answer: Lactic acidosis

Flashcard 64: _____ is the antidote for benzodiazepine toxicity. However, it is not routinely used due to increased risk of seizures

Answer: Flumazenil

Flashcard 65: _____ is the antidote for heparin toxicity

Answer: Protamine sulphate

Flashcard 66: If salicylate poisoning does not respond to urinary alkalinisation with IV sodium bicarbonate then patients my be treated with _____

Answer: haemodialysis

Flashcard 67: Prior to administration of naloxone, initial managment of opioid overdose should involve _____ and oxygen

Answer: airway managment

Flashcard 68: What is the management of cerebral oedema in a patient with carbon monoxide poisoning? _____

Answer: IV mannitol

Flashcard 69: There is limited evidence to suggest that _____ may increase excretion of lithium by increasing the alkalinity of the urine

Answer: IV sodium bicarbonate

Extra: Lithium is handled similarly to sodium in the kidneys. Sodium bicarbonate provides a sodium load which competes with lithium for reabsorption in the proximal tubule, thereby increasing lithium clearance. Note: Hemodialysis is the definitive treatment for severe lithium toxicity.

Flashcard 70: The most severe features of salicylate poisoning are _____ & coma

Answer: seizures