Safe Prescribing — Flashcards

Flashcard 11: Which anti-hypertensive should you avoid prescribing in a patient with HbA1c 63mmol/mol?

Answer: Thiazide-like diuretics (e.g., Indapamide, Chlortalidone) or Thiazide diuretics (e.g., Bendroflumethiazide) :: Thiazide/Thiazide-like diuretics

Extra: Thiazide and thiazide-like diuretics can impair glucose tolerance and worsen glycemic control in patients with diabetes mellitus (HbA1c >48 mmol/mol). ACE inhibitors or Angiotensin Receptor Blockers (ARBs) are generally the first-line antihypertensives for diabetic patients due to their renoprotective effects.

Flashcard 12: What is the reversal agent of the anticoagulant effects of dabigatran?

Answer: • Idarucizumab

Flashcard 13: What medication can cause ototoxicity?

Answer: • Loop diuretics

Flashcard 14: What is Red Man Syndrome?

Answer: • Adverse reaction of IV vancomycin use • symptoms (flushing, pruritis, burning)

Flashcard 15: What medication can cause hypercalcaemia?

Answer: • Thiazide diuretics

Flashcard 16: What is the management of Red Man Syndrome?

Answer: • Cessation of the vancomycin infusion • When symptoms have resolved -> recommencement at a slower rate

Flashcard 17: What type of infections is Vancomycin used to treat?

Answer: • Gram-positive • particularly MRSA

Flashcard 18: Paracetamol overdose >150mg/kg presenting _____ hours post-ingestion is managed with NAC

Answer: 8-24

Flashcard 19: Lithium toxicity can cause _____

Answer: 1st degree heart block

Flashcard 20: How can opioid overdose affect body temperature? _____

Answer: Hypothermia