Rheumatology & Haematology — Flashcards

Flashcard 701: _____% of Hodgkin's lymphoma is associated with EBV infection

Answer: 40

Flashcard 702: Lymphomas commonly present with _____, B symptoms and pruritus

Answer: unexplained lymphadenopathy

Flashcard 703: Organise a 2-week-wait referral for patients with _____ or Bence-Jones protein urine test results suggestive of myeloma

Answer: serum protein electrophoresis

Flashcard 704: Diagnostic criteria for MGUS in patients with serum paraprotein: 1. _____ 2. Monoclonal plasma cells in bone marrow <10% 3. Absence of symptoms (or organ involvement)

Answer: Serum paraprotein <30 g/L

Flashcard 705: Induction therapy prior to stem cell transplantation in myeloma involves a combination of: 1. _____ 2. Chemotherapy (e.g. cyclophosphamide) 3. Steroids (e.g. dexamethasone)

Answer: Targeted immunomodulatory drugs (e.g. thalidomide or bortezomib)

Flashcard 706: Immunoglobulin light chains in the urine of a patient with myeloma are known as _____

Answer: Bence-Jones proteins

Flashcard 707: Myeloma patients at risk of infection may be given _____

Answer: prophylactic antibiotics

Flashcard 708: The clinical features of myeloma can be memorised using the _____ mnemonic.

Answer: CRAB

Extra: Clinical features of Multiple Myeloma (CRAB): - **C**: Calcium (Hypercalcaemia) - **R**: Renal insufficiency - **A**: Anemia - **B**: Bone lesions (Lytic lesions, fractures)

Flashcard 709: What is the management of myeloma? _____

Answer: Autologous stem cell transplant

Flashcard 710: _____ lymphoma is much more common

Answer: Non-Hodgkin's