Rheumatology & Haematology — Flashcards

Flashcard 531: What antibodies can be tested for in suspected rheumatoid arthritis? - _____ - anti-cyclic citrullinated peptide (anti-CCP)

Answer: Rheumatoid factor

Flashcard 532: One complication of long standing rheumatoid arthritis is _____ of the cervical spine

Answer: subluxation

Flashcard 533: Gout has a _____-onset, severely painful joint

Answer: rapid

Flashcard 534: What scoring criteria can be used for rheumatoid arthritis severity? _____

Answer: DAS28; often used to monitor treatment efficacy

Flashcard 535: What is the first-line investigation for pseudogout? _____

Answer: Synovial fluid analysis

Flashcard 536: What is the likely diagnosis in a patient with diffuse musculoskeletal pain that worsens with weather changes, psychological stress, or reduced sleep? _____

Answer: Fibromyalgia

Flashcard 537: What is the acute management for pseudogout? _____, colchicine, or NSAIDs

Answer: Intra-articular steroids

Flashcard 538: What is the first-line pharmacological management for fibromyalgia? _____

Answer: Amitriptyline

Extra: Pharmacological management of Fibromyalgia components: 1. TCAs: Amitriptyline (often used at low doses at bedtime) 2. SNRIs: Duloxetine or Milnacipran 3. Gabapentinoids: Pregabalin 4. Note: Opioids and Corticosteroids are generally avoided.

Flashcard 539: Spot diagnosis: Symmetrical arthritis of small joints with _____, swan-neck, and boutonnière deformities = Rheumatoid arthritis

Answer: ulnar deviation

Extra: Classic hand deformities in Rheumatoid Arthritis (RA) include: - Ulnar deviation of the MCP joints. - Swan-neck deformity: Hyperextension of PIP and flexion of DIP. - Boutonnière deformity: Flexion of PIP and hyperextension of DIP.

Flashcard 540: What is the specialist management for rheumatoid arthritis? 1st-line: _____ 2nd-line: 2x cDMARD combination 3rd-line: Biologics ± cDMARD

Answer: cDMARD