Rheumatology & Haematology — Flashcards

Flashcard 521: _____ is a crystal arthropathy caused by monosodium urate crystals forming in synovial joints and tissues

Answer: Gout

Flashcard 522: What is the first-line investigation for pseudogout? _____

Answer: Synovial fluid analysis

Flashcard 523: What scoring criteria can be used for rheumatoid arthritis severity? _____

Answer: DAS28; often used to monitor treatment efficacy

Flashcard 524: In the management of gout, the target serum urate level is < _____ micromol/L (6 mg/dL)

Answer: 360

Extra: Note: Hyperuricemia alone is NOT diagnostic of gout. The gold standard for diagnosis is the presence of negatively birefringent needle-shaped crystals in synovial fluid.

Flashcard 525: What is the first-line pharmacological management for fibromyalgia? _____

Answer: Amitriptyline

Extra: Pharmacological management of Fibromyalgia components: 1. TCAs: Amitriptyline (often used at low doses at bedtime) 2. SNRIs: Duloxetine or Milnacipran 3. Gabapentinoids: Pregabalin 4. Note: Opioids and Corticosteroids are generally avoided.

Flashcard 526: _____ has a bimodal distribution at 20 and 60 years.

Answer: Hodgkin Lymphoma

Flashcard 527: Pseudogout occurs in adults > _____ years

Answer: 60

Flashcard 528: Rheumatologists may treat rheumatoid arthritis with _____ whilst waiting for DMARDs to take effect

Answer: short-term bridging glucocorticoids

Flashcard 529: Fibromyalgia often presents with "_____"; difficulty concentrating and reduced clarity of thought

Answer: fibro fog

Flashcard 530: What is the prophylactic management for gout? 1st-line: _____ 2nd-line: Febuxostat

Answer: Allopurinol