Rheumatology & Haematology UK Medical PG Flashcards - Medical Study Cards
Master Rheumatology & Haematology with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Rheumatology & Haematology Flashcard Deck - 10 Cards
Flashcard 31: Patients allergic to aspirin may also react to which DMARD?
Answer:
• Sulfasalazine
Flashcard 32: Which HLA allele is most commonly associated with Takayasu Arteritis?
Answer: HLA-B51
Extra: Takayasu arteritis is a large-vessel vasculitis primarily affecting the aorta and its main branches. While it commonly causes renal artery stenosis (a clinical manifestation), it is most notably associated with the HLA-B51 allele (though this association is stronger in Behçet's, it is frequently cited in Takayasu literature along with HLA-B*52).
Note: Renal artery stenosis is a *complication* or *finding* of the disease rather than an associated "condition".
Flashcard 33: Why is folic acid prescribed alongside methotrexate?
Answer: To reduce the risk of methotrexate toxicity, specifically:
• Myelosuppression (most important)
• GI side effects (stomatitis, nausea)
• Hepatotoxicity
Extra: Methotrexate is a folate antagonist (inhibits dihydrofolate reductase). Folic acid supplementation is typically given 24 hours after the weekly methotrexate dose to decrease side effects without compromising efficacy in RA or psoriasis.
Flashcard 34: Young Asian woman with headaches, unequal blood pressure in upper limbs, and claudication, diagnosis?
Answer:
• Takayasu Arteritis
Flashcard 35: What is the classic triad of Fat Embolism Syndrome?
Answer: 1. Respiratory changes -> hypoxia, dyspnea
2. Neurological signs -> confusion
3. Petechial Rash
Flashcard 36: Patient presents with abdominal pain, arthritis, haematuria and a purpuric rash over the buttocks and extensor surfaces of arms and legs, diagnosis?
Answer:
• Henoch-Schonlein purpura
Flashcard 37: How does Sjogren's Syndrome present?
Answer:
• Dry Mouth
• Dry Eyes
• Dry Vagina
*also dry skin, joint pain and stiffness
Flashcard 38: What are the antibodies associated with Sjogren's syndrome?
Answer:
• Anti-Ro
• Anti-La
Flashcard 39: What can acute reactive arthritis be treated with?
Answer:
• NSAIDs
Flashcard 40: What is the imaging of choice for suspected Osteomyelitis?
Answer:
• MRI
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