Rheumatology & Haematology — Flashcards

What is the general management of symptomatic/active chronic lymphocytic leukaemia? _____

Chronic lymphocytic leukemia cause is idiopathic but has a strong _____ link

Chronic lymphocytic leukaemia can cause _____ because of suppression of thrombocytopoiesis

_____ is a myeloproliferative disorder that leads to bone marrow fibrosis, extramedullary haematopoiesis, & splenomegaly

Which blood transfusion reaction can be caused by accumulation of cytokines from donor WBC -or- type II HSR with host antibodies against donor HLA/WBCs? _____

Which blood transfusion reaction is a reaction against donor plasma proteins in transfused blood? _____

What is the likely diagnosis in a patient that develops respiratory distress, hypertension, tachycardia and signs of a heart failure 6-12 hours after a RBC transfusion? _____

Hint: diagnosis?

What is the first step in management for any blood transfusion reaction? _____

What is the most likely diagnosis in a patient who presents days to weeks post-transfusion with worsening Hb after initial improvement and laboratory evidence of hemolysis? _____

Hint: diagnosis?

_____ myelofibrosis occurs as a result of disease progression in patients with previously diagnosed myeloproliferative disorder (e.g. PV, ET)