Rheumatology & Haematology — Flashcards

_____ is the physiological loss of splenic function e.g. in sickle cell anaemia

The management for splenectomy/hyposplenic patients is 2-fold: 1. _____ 2. Prophylactic antibiotics (dependent on risk factors)

Splenectomy/hyposplenism is associated with a long-term risk for sepsis with _____ bacteria

Consider _____ transfusion in bleeding patients with disseminated intravascular coagulation (DIC) & fibrinogen levels < 1-1.5g/L

Disseminated intravascular coagulation (DIC) presents with: _____ platelet count (FBC) ↑ aPTT (coagulation studies) ↑ PT ↓ fibrinogen ↑ D-dimer

Hint: ↑/↓

Patients with splenectomy/hyposplenism should be strongly cautioned of _____ and should take all precautions

Hint: tropical disease

How do lymphocyte levels change post-splenectomy? _____

Why are patients with splenectomy/hyposplenism at risk of encapsulated bacteria? _____

Disseminated intravascular coagulation (DIC) typically presents with _____ bleeding time

Pancytopenia presentation: _____ = fatigue, pallor, dyspnoea Neutropaenia = recurrent or severe infections Thrombocytopenia = ecchymoses, petechiae, gingival bleeding, epistaxis