Rheumatology & Haematology — Flashcards

Antibiotic prophylaxis in splenectomy/hyposplenic patients who are immunocompromised or had previous post-splenectomy sepsis should be taken for _____ year(s)

The management for splenectomy/hyposplenic patients is 2-fold: 1. _____ 2. Prophylactic antibiotics (dependent on risk factors)

In DIC where thrombosis predominates, consider management with _____

Consider _____ transfusion in bleeding patients with disseminated intravascular coagulation (DIC) & fibrinogen levels < 1-1.5g/L

Disseminated intravascular coagulation (DIC) presents with: _____ platelet count (FBC) ↑ aPTT (coagulation studies) ↑ PT ↓ fibrinogen ↑ D-dimer

Hint: ↑/↓

Why are patients with splenectomy/hyposplenism at risk of encapsulated bacteria? _____

_____ occurs due to pathologic activation of the coagulation cascade

What is the management for a haemodynamically unstable patient with a spleen injury? _____

Disseminated intravascular coagulation (DIC) is characterised by widespread _____ formation, resulting in ischaemia & infarction

_____ is a severe form of hyposplenism where the spleen "self destructs" causing physiological loss of splenic function