Iron deficiency is caused by 1. dietary _____ 2. increased iron requirement e.g. growth spurt, pregnancy 3. increased iron loss e.g. GI bleeding from malignancy or peptic ulcer disease, menstrual bleeding, frequent blood donation 4. malabsorption e.g. IBD, coeliac disease, bariatric surgery
What are the three main causes of asplenia/hyposplenism? 1. _____ ~75% 2. Traumatic ~20% 3. Hyposplenism/autosplenectomy ~5%
What is the management for a haemodynamically unstable patient with a spleen injury? _____
Antibiotic prophylaxis for asplenic children should be taken until at least _____ years old
Consider _____ transfusion in bleeding patients with disseminated intravascular coagulation (DIC) & fibrinogen levels < 1-1.5g/L
Patients with splenectomy/hyposplenism should be strongly cautioned of _____ and should take all precautions
Hint: tropical disease
Disseminated intravascular coagulation (DIC) presents with _____ & thrombosis
Disseminated intravascular coagulation (DIC) is associated with thrombosis, resulting in _____ failure
_____ is a severe form of hyposplenism where the spleen "self destructs" causing physiological loss of splenic function
In DIC where thrombosis predominates, consider management with _____
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