Rheumatology & Haematology — Flashcards

Patients with thalassaemias will be offered genetic _____ and family members will be offered screening

Alpha thalassaemia major (haemoglobin Bart's disease) often results in _____ in utero

Public Health England recommend all _____ women are screened for thalassaemia

Haemophilia A can arise from a(n) _____ mutation without any family history (20%)

The most common cause of thrombocythaemia is _____ that is triggered by infection, inflammation, etc

What is the general management for thalassaemia intermedia or haemoglobin H disease (- -/-α)? _____

Petechial bleeding is a common sign of _____ disorders

Hint: coagulation/platelet

Thalassaemia is associated with a(n) _____ red cell distribution width (RDW)

_____ alleles encode for the x2 α-globin chain 2 alleles encode the x2 β-globin chains

Hint: number

FBC for essential thrombocythaemia has sustained isolated _____