Respiratory Medicine — Flashcards

Antigenic variation of influenza viruses occurs with mutations to viral _____ and neuraminidase (NA)

What is the management of uncomplicated influenza patients at ↑ risk? _____

_____ is an acute, contagious viral respiratory infection caused by influenza virus A, B, C (rarely)

Influenza A is named according to _____ & neuraminidase (NA) subtypes

A patient in winter suffers from sudden-onset high fever, cough, headache, & myalgia. O/E patient has a temp. of 39.0°C, tachycardic, & clear lungs. What is the likely diagnosis? _____

Hint: ?diagnosis

What is the management of uncomplicated influenza in healthy patients? _____

An elderly patient with +ve RT-PCR for influenza A develops worsening SOB, oxygen saturations of 88% and bilateral interstitial infiltrates on CXR, what is the likely diagnosis? _____

Hint: ?diagnosis

What is the management of complicated influenza? 1st-line: _____ 2nd-line: Inhaled zanamivir

In influenza the antigen _____ facilitates viral release by cleaving sialic acid

Influenza undergoes antigenic _____ due to point mutations in the hemagglutinin (HA) or neuraminidase (NA) genes resulting in seasonal outbreaks & epidemics