Gastroenterology & Hepatology — Flashcards

Flashcard 681: What is the management for inducing remission in mild-to-moderate ulcerative colitis? 1st-line: _____ Remission not achieved within 4 weeks → add oral 5-ASA

Answer: topical 5-ASA

Flashcard 682: _____ is characterised by full-thickness/transmural inflammation

Answer: Crohn's disease

Flashcard 683: What is an important differential for Crohn's? _____

Answer: Appendicitis

Flashcard 684: Why can Crohn's cause vitamin B12 deficiency? _____

Answer: Damage to the terminal ielum

Flashcard 685: Small bowel obstruction can present with nausea & vomiting, typically _____ vomiting

Answer: bilious

Flashcard 686: When are antibiotics used in perianal abcesses? _____

Answer: If there is systemic upset secondary to the abscess.

Extra: Antibiotics are generally **not** required after I&D of a simple perianal abscess unless there is: 1. Systemic upset (fever, sepsis) 2. Significant spreading cellulitis 3. Diabetes or immunosuppression 4. Risk of endocarditis (valvular heart disease)

Flashcard 687: Crohn's disease is more susceptible to strictures, fistulas, & adhesions because _____

Answer: of transmural inflammation → more complete loss of bowel wall integrity

Flashcard 688: The cause of Crohn's disease is unknown, but there is a strong _____

Answer: genetic susceptibility

Flashcard 689: Smoking results in: _____ risk for Crohn disease ↓ risk for Ulcerative colitis

Answer: ↑

Flashcard 690: Crohn disease is characterised histologically by lymphoid aggregates with _____

Answer: noncaseating granulomas