Gastroenterology & Hepatology — Flashcards

Flashcard 11: Metoclopramide should not be used for more than _____ due to risk of extrapyradimal effects

Answer: 5 days

Extra: Metoclopramide is a D2 receptor antagonist. Extrapyramidal side effects (EPS) are common in young adults and children. Persistent use (>3 months) can lead to irreversible tardive dyskinesia. Contraindicated in pheochromocytoma and gastrointestinal hemorrhage/obstruction.

Flashcard 12: Hirschsprung's disease is an important differential diagnosis in _____

Answer: childhood constipation

Flashcard 13: What is the monoclonal antibody that targets C.difficile toxin B? _____

Answer: bezlotoxumab

Flashcard 14: Hirschsprung's disease is 3 times more common in _____

Answer: males

Flashcard 15: _____ and gabapentin are also used in hiccup prescribing in palliative

Answer: Haloperidol

Flashcard 16: Hirschsprung's Disease is characterized by an _____ due to a failure of neural crest cell migration during development.

Answer: aganglionic segment of bowel

Flashcard 17: Possible presentation of Hirschsprung's disease in older children is _____

Answer: Constipation, abdominal distension

Flashcard 18: Vast majority of children with consitpation have _____

Answer: no identifiable cause

Flashcard 19: Possible presentation of Hirschsprung's disease in the neonatal period is _____

Answer: failure or delay to pass meconium

Flashcard 20: Hirschsprung's disease is associated with _____

Answer: Down's syndrome