Endocrinology & Diabetes — Flashcards

Clinical features of _____ include moon facies, buffalo hump, and truncal obesity due to increased fat storage, secondary to excess insulin

High dose dexamethasone suppression test: _____ cortisol ↑ ACTH = Ectopic ACTH (small cell lung cancer)

Hint: ↓/↑

One clinical feature seen in women with Cushing's syndrome is _____ as a result of increased androgen levels

High dose dexamethasone suppression test: _____ cortisol ↓ ACTH = Adrenal adenoma

Hint: ↓/↑

What is the management of Cushing's disease if trans-sphenoidal surgery / radiation fails? _____

High dose dexamethasone suppression test: ↓ cortisol = _____

One clinical feature of Cushing syndrome is muscle weakness with _____ extremities

Hint: appearance

What investigation is used to localise the pathology causing Cushing's disease? _____

One clinical feature of Cushing syndrome is _____, which is a result of decreased osteoblast activity

Cushing's disease causes _____ obesity as well as redistribution of adipose tissue causing moon face and buffalo hump