Endocrinology & Diabetes — Flashcards

One clinical feature of Cushing syndrome is muscle weakness with _____ extremities

Hint: appearance

What investigation is used to help differentiate/localise the pathology in Cushing's disease from ectopic ACTH? \n_____

One clinical feature seen in women with Cushing's syndrome is _____ as a result of increased androgen levels

What is the management of Cushing's disease if trans-sphenoidal surgery / radiation fails? _____

High dose dexamethasone suppression test: ↓ cortisol = _____

One clinical feature of Cushing syndrome is abdominal striae which is a result of impaired _____ synthesis, allowing blood vessels to rupture easily

Clinical features of _____ include moon facies, buffalo hump, and truncal obesity due to increased lipogenesis/fat storage, secondary to excess insulin levels (compensatory).

High dose dexamethasone suppression test:\n_____ cortisol + Low/Suppressed ACTH = Adrenal tumor (Adenoma/Carcinoma)

One clinical feature of Cushing syndrome is _____, which is a result of decreased osteoblast activity

In **asymptomatic** patients, a diagnosis of Type 2 Diabetes requires _____ abnormal test results (HbA1c or Plasma Glucose) obtained on separate occasions.