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Endocrinology & Diabetes — Flashcards

Endocrinology & Diabetes — Flashcards

Endocrinology & Diabetes — Flashcards

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662 flashcards— Page 56 of 67
#551

T1DM is associated with the genetic variants _____ and HLA-DR4

#552

DKA primarily affects patients with _____, but can rarely affect patients with type 2 diabetes

#553

Which of the following are clinical features typically found in DKA but **not** in HHS?\n\n• _____\n• Hyperventilation/Kussmaul breathing\n• Pear drop breath (acetone)

#554

There is no specific criteria, but HHS typically presents with: • Serum glucose: _____ mmol/L • Serum osmolarity: significantly raised • Ketones: Normal (<3 mmol/L) • pH: Normal (>7.3)

#555

_____ is the most important electrolyte to consider in DKA. DKA causes an intracellular deficit of potassium

#556

_____ and short acting insulins have a quick onset and short duration. They are used to replicate insulin spikes in response to glucose from a meal or sugar\nIntermediate and long acting insulins have a slow onset and long duration. They are used to replicate endogenous basal insulin secreted continuously throughout the day

#557

HHS is caused by insufficient _____ which may be precipitated by illness or medications

#558

HHS pathophysiology is predominantely characterised by severe _____

#559

_____ is much more profound in HHS due to later presentation

Hint: Clinical feature

#560

Insulin therapy for HHS SHOULD NOT begin until _____ UNLESS there is significant ketonemia (or DKA).

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