Endocrinology & Diabetes — Flashcards

The most common cause of osteomalacia/rickets is _____

Bone pain, muscular/bone tenderness, pathological fractures and waddling gait in adults with _____ deficiency is likely to be osteomalacia

In patients with primary hyperparathyroidism where a parathyroidectomy is not feasible/unsuccessful, patients may be offered _____

_____ is the most common cause of hypothyroidism worldwide

Subacute granulomatous thyroiditis (De Quervain's) presents initially with _____thyroidism followed by hypothyroidism before full recovery

Following diagnosis of hyperparathyroidism, patients should have further investigations to screen for complications such as _____, DXA scan (lumbar spine, distal radius, hip), USS of the renal tract

Hint: Nephrocalcinosis

Vitamin D-dependent rickets type _____ is an autosomal recessive condition characterised by a mutation causing end organ resistance to vitamin D

Hint: 1/2

Rickets is caused by decreased mineralization of _____ at epiphyseal growth plates

PTH induces _____ expression in osteoBlasts which binds to and activates osteoClasts

Hypercalcaemia increases the risk of _____ due to polyuria and reduced oral intake