Renal Physiology — Flashcards

Na+ is reabsorbed in the _____ via the Na+-K+-2Cl- cotransporter in the luminal membrane

How does ADH increase H2O permeability of the principal cells of the late distal tubule and collecting duct?Increased _____ channels via increased cAMP

The H2CO3 formed inside the cells of the PCT dissociates into _____ and HCO3-

In the presence of _____, aquaporin 2 channels are inserted in the luminal membrane of principal cells of the late distal tubule and collecting duct

In the cells of the proximal tubule, the enzyme _____ metabolizes glutamine to glutamate and NH4+

In response to increased Na+ delivery (e.g. increased GFR/RPF), the macula densa releases _____, which constricts the afferent arterioles

Decreases in _____ (e.g. hemorrhage or decreased Na+) cause a decrease in renal perfusion pressure, which in turn increases secretion of the enzyme renin

HCO3- is transported across the basolateral membrane into the blood by:\n1. Proximal tubule: _____\n2. Alpha-intercalated cells: Cl--HCO3- exchange

Some _____ in the cells of the thick ascending limb diffuse back into the lumen, creating a lumen positive potential difference

In the _____ of the nephron, 50% of the filtered urea is reabsorbed by simple diffusion