Renal Physiology — Flashcards

The H2CO3 formed inside the cells of the PCT dissociates into _____ and HCO3-

In the presence of _____, aquaporin 2 channels are inserted in the luminal membrane of principal cells of the late distal tubule and collecting duct

The primary regulation of aldosterone secretion occurs through changes in _____ (via the renin-angiotensin II-aldosterone system) and changes in serum potassium levels

HCO3- is transported from the cells of proximal tubule into the blood by _____ cotransport and Cl--HCO3- exchange

In the _____ of the nephron, urea is secreted by simple diffusion

Some _____ in the cells of the thick ascending limb diffuse back into the lumen, creating a lumen positive potential difference

How does ADH increase H2O permeability of the principal cells of the late distal tubule and collecting duct?Increased _____ channels via increased cAMP

Na+ is reabsorbed in the _____ via the Na+-K+-2Cl- cotransporter in the luminal membrane

Decreases in _____ (e.g. hemorrhage or decreased Na+) cause a decrease in renal perfusion pressure, which in turn increases secretion of the enzyme renin

In the cells of the proximal tubule, the enzyme _____ metabolizes glutamine to glutamate and NH4+