Blood and Immunity — Flashcards

Flashcard 81: The spleen normally sequesters _____% of the body's platelets

Answer: 30% to 35% (approx. 1/3)

Flashcard 82: When does the switch from HbF to HbA synthesis begin?

Answer: 30 weeks of intrauterine life

Flashcard 83: SulphHb will lead to a falsely _____ reading on pulse oximeter

Answer: low

Extra: Sulfhemoglobin (SulphHb) absorbs light at the 660 nm wavelength (similar to deoxyhemoglobin and methemoglobin). This interference causes the pulse oximeter to underestimate oxygen saturation, resulting in a falsely low SpO2 reading.

Flashcard 84: Nurse cells are specialized _____ in bone marrow that assist in the development of red blood cells

Answer: macrophages

Flashcard 85: Methemoglobin leads to a pulse oximeter reading that is falsely _____

Answer: low (typically ~85%)

Flashcard 86: Macrophages participate in the _____ phase of humoral immunity by efficiently phagocytosing and destroying microbes that are opsonized (coated) with IgG or C3b.

Answer: effector

Flashcard 87: Transport of CO is diffusion limited because of the high affinity of CO to _____, thus preventing rise in the partial pressure of CO

Answer: hemoglobin

Flashcard 88: The major source of plasma von-Willebrand factor are _____

Answer: endothelial cells

Flashcard 89: Basophils are activated by IL-_____ and IL-_____

Answer: 5; 3

Flashcard 90: B-Lymphocytes undergo affinity maturation in the _____ of Lymph node.

Answer: germinal center