Endocrine Pharmacology — Flashcards

_____ and perchlorate are competitive inhibitors of the Na+-I- cotransport pump, thus interfering with the synthesis of thyroid hormones

One mechanism by which metformin decreases gluconeogenesis is via _____ of the enzyme AMP-activated protein kinase (AMPK)

Thyroid, Pituitary, & Adrenal _____ is a GH receptor antagonist, which may be used to treat acromegaly

Exogenous testosterone causes _____ LDL and decreased HDL

Thyroid, Pituitary, & Adrenal _____ are a class of drugs that are useful in the treatment and prevention of postmenopausal osteoporosis

_____ inhibitors, such as finasteride may be used to treat benign prostatic hyperplasia because they block activation of testosterone (to DHT) in the prostate

_____ is an anti-progestin used to terminate pregnancy when combined with misoprostol (PGE1 analog)

Monotherapy of _____ and insulin have a weight-gain effect.

Drugs _____ binding of thyroxine to thyroxine binding globulin: Steroids, Salicylates and Androgens

Absolute contraindications to combined oral contraceptive use: Known or suspected carcinoma of the _____, female reproductive tract