Endocrine Pharmacology — Flashcards

Flashcard 101: Fastest acting anti-thyroid drugs are: drugs inhibiting _____

Answer: thyroid hormone release

Flashcard 102: _____ is a dual SGLT-1/2 inhibitor

Answer: Sotagliflozin

Flashcard 103: Which insulin should not be mixed in the same syringe with other insulins, and why?

Answer: Insulin glargine; because it is an acidic solution (pH 4.0) and will precipitate at neutral pH, which alters its absorption profile.

Flashcard 104: What is the drug used in rx of CAH in a child?_____

Answer: Hydrocortisone

Flashcard 105: _____ may be given with Carbimazole or a beta-blocker 10 days before the operation, to reduce vascularity and increase margin of safety

Answer: Iodine

Flashcard 106: Steroid receptor antagonist that can be used in Cushings syndrome is _____

Answer: mifepristone

Flashcard 107: _____ is an anti-estrogenic, anti-progestational, and mildly anabolic drug which acts as a 19-nortestosterone derivative similar to danazol, but with fewer side effects

Answer: Gestrinone

Flashcard 108: Most injectable GnRH antagonists (e.g., Cetrorelix, Ganirelix, Degarelix) are administered _____.

Answer: subcutaneously

Extra: Note: **Relugolix** and **Elagolix** are **oral** GnRH antagonists. **Abarelix** is administered intramuscularly (IM).

Flashcard 109: _____ is a NK3R antagonist approved for treatment of hot flushes in post menopausal women.

Answer: Fezolinetant

Flashcard 110: Which antithyroid drug has been associated with fetal aplasia cutis?_____

Answer: Methimazole