Neuropathology — Flashcards

_____ matter lesions are common in tuberous sclerosis and include nodules, cysts, and areas of gliosis and hypomyelination

Classical histological finding in progressive supranuclear palsy will be ballooned neurons and "tufted astrocytes" in the _____ lobes

In patients with cerebral involvement, Gaucher cells are seen in the _____ spaces.

What is the classical pathology seen in a kid of spastic diplegia?_____

Arteries in CADASIL, may show basophilic, periodic acid Schiff (PAS)-_____ deposits, which contain the NOTCH3 protein

_____ are the earliest morphologic markers of neuronal cell death

For the diagnosis of oligodendroglioma, it is essential to have both IDH mutation and _____ codeletion

What is the most common type of astrocytoma in children?_____

Most cases of secondary glioblastoma, with a prior hx of lower-grade diffuse glioma are of the IDH-_____ type.

The most common cytogenetic abnormality in meningioma is _____