Inflammation and Repair — Flashcards

Important neutrophil chemotactants include:a. C5ab. IL-8c. LTB4d. _____e. platelet-activating factor

Wound _____ may occur when there is unusually pronounced MMP activity and myofibroblast accumulation in wound margins

Fever in inflammation is mediated by release of _____, TNF and IL-6 by macrophages in response to pyrogens (e.g. LPS from bacteria)

Acute inflammation arises in response to _____ or tissue necrosis

A _____ lies beneath an intact epidermis and consists of an extravascular collection of blood that has leaked from blood vessels damaged by mechanical impact

_____ produce major basic protein, which destroys parasites and is responsible for epithelial cell damage in asthma

In the setting of chronic inflammation, macrophages can be activated to M1 macrophages by stimulation from _____ cells, resulting in a proinflammatory phenotype

During leukocyte margination, leukocytes marginate from the _____ of flow to the periphery (center or periphery)

Toluidine blue is the special stain for _____ cells.

The most common mechanism of vascular leakage in acute inflammation is the _____ of endothelial cells