Immunopathology — Flashcards

_____ is caused by cross-reactivity between Streptococcus pyogenes (GAS) antigens (M protein) and self-antigens

_____ cells are identified by expression of CD3, CD4, CD25, and FOXP3

_____ amyloidosis is characterized by systemic deposition of AL amyloid, which is derived from Ig light chain

Atypical HUS is often associated with defects in complement _____, membrane cofactor protein (CD46), and factor I

LE cell is a phagocytic _____ or macrophage that has engulfed the denatured nucleus of an injured cell

_____ is an antiphospholipid antibody that may result in false-positive VDRL and RPR tests

In type III HSRs, antigen-antibody complexes activate _____, which attracts neutrophils

_____ is an IgM autoantibody against Fc portion of IgG

_____ or peripheral staining may reflect antibodies to double-stranded DNA and sometimes to nuclear envelope proteins

Cytotoxic T cells may induce apoptosis of target cells via release of _____ and granzymes, which leads to activation of caspases