Bone and Soft Tissue Pathology — Flashcards

_____ may present with blue sclerae due to translucent connective tissue over choroidal veins

_____myositis is characterized by endomysial inflammation with necrotic muscle fibers on biopsy

_____ may occur due to carbonic anhydrase II mutations, which leads to loss of the acidic environment necessary for bone resorption

X-linked osteopetrosis occurs due to mutation in the _____ gene and is associated with anhidrotic ectodermal dysplasia.

In osteoporosis, cytokines stimulate osteoclast recruitment and _____ the levels of RANKL and decrease the expression of osteoprotegerin

_____ is characterized by perimysial inflammation with perifascicular atrophy on biopsy.

Histology of adamantinoma shows _____ islands in a fibrous stroma

_____ and osteoid osteoma do not contain giant cells.

In adults, woven bone is seen _____ and in Paget disease.

_____ tumor is a fibroadenoma-like tumor with overgrowth of the fibrous component, causing 'leaf-like' projections