Maternal-Fetal Medicine — Flashcards

Flashcard 51: Spontaneous abortion is most often due to _____ anomalies, especially trisomy 16

Answer: chromosomal

Flashcard 52: Protocol for Rh isoimmunization: If the blood group of the husband is Rh-positive and the maternal ICT is negative, there is no _____; prevention is achieved by giving anti-D prophylaxis at 28 weeks.

Answer: isoimmunization

Flashcard 53: Placental abruption typically presents with abrupt, _____ third trimester bleeding

Answer: painful

Flashcard 54: Protocol for Rh isoimmunization: If **MCA-PSV** is _____ than 1.5 deliver at 37 completed weeks

Answer: less

Extra: In Rh isoimmunization, the **Middle Cerebral Artery Peak Systolic Velocity (MCA-PSV)** is monitored to detect fetal anemia. - **< 1.5 MoM**: Suggests mild or no anemia. If it remains below this threshold, delivery is typically recommended at **37–38 weeks**. - **≥ 1.5 MoM**: Suggests severe fetal anemia; requires further investigation (cordocentesis) and potential intrauterine transfusion (IUT). Note: The term "Critical Titer" refers to antibody levels (e.g., 1:16), not the MoM value.

Flashcard 55: How does coagulability change during pregnancy? _____

Answer: Increases (hypercoagulable state)

Flashcard 56: Protocol for Rh isoimmunization:If on Fetal blood sampling, the hematocrit is <_____, do Intrauterine transfusion.

Answer: 30

Flashcard 57: A _____ hydatidiform mole is characterized by 46 chromosomes

Answer: complete

Flashcard 58: _____ system: Grading of Abruptio placentae

Answer: Sher and Page

Flashcard 59: Ectopic pregnancy may present with a _____ than expected rise in the hormone hCG based on dates

Answer: lower

Flashcard 60: If the developing embryo splits during **days 8-12** (after the amnion has formed), the twins will be _____ and monoamniotic (# of chorions and # of amniotic sacs)

Answer: monochorionic

Extra: Timing of Monozygotic Twinning: - **Days 0-4**: Dichorionic / Diamniotic (Cleavage stage) - **Days 4-8**: Monochorionic / Diamniotic (Blastocyst stage) - **Days 8-12**: Monochorionic / Monoamniotic (Embryonic disc stage) - **>13 Days**: Conjoined twins